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Peptide Fragments

BPC-157

Also written BPC157 · BPC 157

BPC-157 is a synthetic 15-amino-acid peptide (pentadecapeptide, GEPPPGKPADDAGLV) supplied in the UK by British Peptide Labs as a ≥99% purity (HPLC) lyophilised powder in a sealed 10 mg vial, for in-vitro laboratory research. Its sequence corresponds to a fragment of Body Protection Compound, a larger peptide first isolated from human gastric juice.

In stock
10 mg vial£30.00

£3.00 per mg

≥99% purity (HPLC) · Independent third-party testing by PeptideVerify · COA Library

Order before 3pm for same-day dispatch.

Cut-off 3pm, Mon–Sat

Free next-day tracked delivery on every order · Royal Mail Tracked 24

10 mg · £30.00 · £3.00/mg

BPC-157 in the UK: key facts

What it is
Synthetic 15-amino-acid peptide (pentadecapeptide) · Peptide Fragments research area
Name
BPC-157 (Body Protection Compound-157 fragment)
Sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV)
Molecular formula · weight
C62H98N16O22 · 1419.53 g/mol
CAS number
137525-51-0
Form
White to off-white lyophilised powder, sealed 10 mg vial
Purity
≥99% (HPLC)
Testing
Independent third-party testing by PeptideVerify (HPLC + LC-MS) · reports in the COA Library
Price
£30.00 per 10 mg vial (£3.00 per mg)
Dispatch
Order by 3pm Mon–Sat for same-day dispatch; next-day tracked delivery (Royal Mail Tracked 24)
Supplier
British Peptide Labs, trading name of AODAEMON LTD, UK-registered company (Companies House 17176945)
Sport classification
WADA Prohibited List, S0 (non-approved substances)

About BPC-157

BPC-157 is a synthetic linear pentadecapeptide: fifteen amino acid residues, H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH, with a free amine at the N-terminus and a free carboxylic acid at the C-terminus. The sequence corresponds to a fragment of a larger peptide from gastric juice. Four of the fifteen residues are proline, three of them consecutive, and the chain carries three acidic side chains against a single lysine.

There is no cyclisation, lipidation or non-proteinogenic residue, so identity rests on sequence and mass: CAS number 137525-51-0, the molecular formula C62H98N16O22 and a molecular weight of 1419.53 g/mol. With no aromatic residue, the peptide absorbs mainly in the peptide-bond region around 214 nm, so reversed-phase HPLC with low-wavelength ultraviolet detection gives its profile and mass spectrometry confirms the expected mass. Each presentation is supplied as a lyophilised powder in a sealed vial.

Identifiers

  • PubChem CID 9941957

Further reading

BPC-157 structure and analytical profile

In one-letter code the chain reads GEPPPGKPADDAGLV, from Gly1 to Val15. Its fifteen residues are all coded L-amino acids apart from glycine, which has no stereocentre, and they fall into a few clear groups: four prolines (positions 3, 4, 5 and 8), three glycines (1, 6 and 13), two alanines, two aspartic acids, and one each of glutamic acid, lysine, leucine and valine.

The Pro-Pro-Pro run at positions 3 to 5 is the chain's most distinctive feature. Prolines lock the backbone angle at each of those positions, and the peptide bonds in front of them can sit in the cis or the trans form, which is why a proline-rich chain can show a slightly broadened main peak in HPLC without any change in composition.

Glycines at positions 1, 6 and 13 give the chain three flexible points, and the two alanines and the closing Leu-Val pair supply its only aliphatic side chains besides proline. The sequence has no cysteine, methionine or tryptophan, so it carries no disulfide bridge and no easily oxidised residue.

Both ends are unmodified: Gly1 keeps a free amine and Val15 a free carboxylic acid, so there is no acetyl cap and no C-terminal amide. With three acidic side chains, Glu2, Asp10 and Asp11, plus the C-terminal carboxyl, against one lysine and the N-terminal amine, the calculated net charge near pH 7 is about −2.

That acidic character shapes the analysis. In positive-mode electrospray the chain gives singly and doubly protonated ions, while the low pH of a typical reversed-phase mobile phase protonates the carboxyl groups during HPLC, so the chain runs as a neutral-to-cationic species on the column.

The monoisotopic mass is 1418.7042 Da, so the [M+H]+ ion is expected at m/z 1419.7114 and the [M+2H]2+ ion at m/z 710.3594. A deletion sequence missing one proline would sit 97.05 Da lower, and one missing a glycine 57.02 Da lower, so the mass spectrum separates the full chain from the likeliest synthesis by-products at once.

The formula C62H98N16O22 gives an average molecular weight of 1419.53 g/mol, about 0.83 Da above the monoisotopic value, because the heavier isotopes of carbon, hydrogen, nitrogen and oxygen are averaged in.

HPLC at around 214 nm gives purity as the main peak's share of total peak area, at ≥99% (HPLC) for this product. The material is a white to off-white lyophilised solid in a sealed vial. The sealed vial is stored at 2–8 °C short term, or at −20 °C and below for long-term storage, protected from light and away from repeated freeze-thaw cycles.

Buying BPC-157 in the UK

Order BPC-157 directly from British Peptide Labs, a UK-registered company, as a sealed vial in 10 mg presentation, from £30. Every size is listed below with its vial price and its price per mg, so the presentations compare at a glance.

BPC-157 price (UK)
PresentationPrice£/mg
BPC-157 10 mg£30.00£3.00

Choose a presentation in the buy box, add it to your basket and check out. Orders placed before 3pm Mon–Sat are packed the same working day and handed to Royal Mail Tracked 24, and your tracking number is emailed as soon as the parcel leaves us. Larger orders are welcome: add as many vials as your laboratory needs in a single basket.

For what other UK suppliers charge, see our UK price per mg data, updated every month.

Product information

Synonym
BPC157, BPC 157, Body Protection Compound-157
CAS number
137525-51-0
Molecular formula
C62H98N16O22
Molecular weight
1419.53 g/mol
Sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Appearance
White to off-white lyophilised powder
Purity
≥99% (HPLC)
Net content
10 mg per vial
Storage (sealed vial)
Store at 2–8 °C short term, or at −20 °C and below for long-term storage. Protect from light and avoid repeated freeze-thaw cycles
Sequence (one-letter)
GEPPPGKPADDAGLV
PubChem CID
9941957
Testing
Independent third-party testing by PeptideVerify (HPLC + LC-MS)
WADA classification
S0, non-approved substances
Residues
15
Monoisotopic mass
1418.7042 Da
Expected [M+H]+
m/z 1419.7114
Net charge near pH 7
−2.0
Research use
For laboratory research use only. Not for human or veterinary use.

BPC-157 is a synthetic 15-amino-acid peptide (pentadecapeptide, GEPPPGKPADDAGLV) supplied in the UK by British Peptide Labs as a ≥99% purity (HPLC) lyophilised powder in a sealed 10 mg vial, for in-vitro laboratory research. Its sequence corresponds to a fragment of Body Protection Compound, a larger peptide first isolated from human gastric juice. Store the sealed vial at 2–8 °C for short-term storage, or at −20 °C and below for long term. Protect from light and avoid repeated freeze-thaw cycles. For research use only. Not for human or veterinary use. Sold strictly for in-vitro laboratory research; not for diagnosis or treatment.

Packing
Each sealed vial travels in protective packing.
Dispatch
Orders placed before 3pm Mon–Sat leave the same day.
Delivery
Next-day tracked delivery with Royal Mail Tracked 24.
Tracking
Your tracking number is emailed as soon as the order is dispatched.
Delivery cost
Delivery is free on every order.
Shipping details

Questions about BPC-157

BPC-157 is a synthetic 15-amino-acid peptide (pentadecapeptide) with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. Its sequence corresponds to a fragment of Body Protection Compound, a larger peptide first isolated from human gastric juice.

Read the Learn article

BPC-157 has the molecular formula C62H98N16O22, a molecular weight of 1419.53 g/mol and CAS number 137525-51-0. In one-letter code the sequence is GEPPPGKPADDAGLV.

British Peptide Labs supplies BPC-157 as a lyophilised powder in a sealed 10 mg vial for £30.00. Orders placed by 3pm Mon–Sat are dispatched the same day with next-day tracked delivery by Royal Mail Tracked 24, free to any UK address.

Yes. Our BPC-157 has independent third-party testing by PeptideVerify, using HPLC for purity and LC-MS for identity, and is ≥99% purity (HPLC). PeptideVerify reports are published in the COA Library.

Open the COA Library

White to off-white lyophilised powder in a sealed 10 mg vial. Store at 2–8 °C short term, or at −20 °C and below for long-term storage. Protect from light and avoid repeated freeze-thaw cycles.

Buyers aged 18 and over. At checkout every buyer accepts our Terms and Conditions and confirms in-vitro research use only.

Read the Terms and Conditions

Yes, as the BPC-157 / TB-500 Mix, a co-lyophilised 20 mg blend of the two peptides in one sealed vial.

BPC-157 / TB-500 Mix

Order by 3pm Mon–Sat for same-day dispatch; Royal Mail Tracked 24 delivers the next working day after dispatch.

Shipping details

Yes. BPC157 and BPC 157 are other spellings of BPC-157: the same fifteen-residue peptide, GEPPPGKPADDAGLV, with CAS number 137525-51-0 and the formula C62H98N16O22.

1418.7042 Da, calculated from the formula C62H98N16O22. In positive-mode electrospray the [M+H]+ ion is expected at m/z 1419.7114 and the [M+2H]2+ ion at m/z 710.3594. The average molecular weight, 1419.53 g/mol, sits about 0.83 Da higher because it averages in the heavier isotopes.

About −2. Three acidic side chains (Glu2, Asp10 and Asp11) and the free C-terminal carboxyl outweigh the single lysine and the N-terminal amine, and the chain has no histidine or arginine. The figure comes from the standard side-chain pKa values of the residues in the sequence GEPPPGKPADDAGLV.

Four, at positions 3, 4, 5 and 8. The first three form a Pro-Pro-Pro run, which gives the chain its rigid N-terminal segment and can broaden the HPLC main peak slightly through cis and trans peptide bonds. They account for four of the fifteen residues, more than a quarter of the chain.

Because it has no tryptophan, tyrosine or phenylalanine, so it barely absorbs at 280 nm. At around 214 nm every peptide bond absorbs, which gives a strong, quantifiable signal for the main peak and its related substances.

BPC-157 is catalogued in the Peptide Fragments research area, where compounds are grouped by molecular class. The research area page lists each of them with its identifiers.

Peptide Fragments research area